Critically evaluate the current methods of high-throughput expression Essay

Critically evaluate the current methods of high-throughput expression profiling in normal and disease states - Essay Example These studies have provided information that was challenging to find, making it easy to detect diseases very early and applying the necessary intervention and treatment procedures on time reducing rates of morbidity and mortality. The first step n the quest to understand the cell function would be understanding gene expression of the various cells of the body. In that case, it would be easier to determine when cells are not expressed as expected. Scientists and researchers point out that gene expression anomalies mostly involve the Messenger RNA (mRNA). DNA Microarrays are used to measure the expression of cells within a predefined mRNA. Different cells are expected to be expressed in a certain way in the mRNA. Changes in expression include over-expression or under-expression. For example, scientists have confirmed that breast cancer cells express more mRNA for the membrane receptor (Suter, Babiss and Wheeldon, 2004).